Acqua Toffana

Aqua Tofana (also known as Acqua Toffana and Aqua Tufania and Manna di San Nicola) was a strong poison created in Sicily around 1630 that was reputedly widely used in Palermo, Naples, Perugia, and Rome, Italy. It has been associated with Giulia Tofana, or Tofania, a woman from Palermo, purportedly the leader of a ring of six poisoners in Rome, who sold Aqua Tofana to would-be widows.